Urology Practice Management - September 2020, Vol 6, No 3

Interim analysis of the phase 3 JAVELIN Bladder 100 clinical trial showed that maintenance therapy with the PD-L1 inhibitor avelumab (Bavencio) plus best supportive care significantly prolonged overall survival (OS) versus best supportive care alone in patients with advanced urothelial carcinoma whose disease did not progress with first-line platinum-based chemotherapy. Read More ›

New research highlights the importance of germline analysis in the identification of germline alterations for cancer treatment. Read More ›

Since the emergence of COVID-19, the Centers for Medicare & Medicaid Services (CMS) engaged in an unprecedented effort to utilize telemedicine as one of the primary weapons against the disease. Read More ›

Adjuvant therapy with atezolizumab (Tecentriq) did not meet the primary end point of disease-free survival (DFS) in patients with muscle-invasive urothelial cancer (MIUC) at high risk for recurrence versus observation alone in the primary analysis of the IMvigor010 trial. Read More ›

An analysis of the Value Framework of the ASCO shows that the Net Health Benefit score of cancer drugs continues to evolve over time after their FDA approval, based on data presented at the ASCO 2020 virtual annual meeting. Read More ›

Early results from the phase 2 TheraP clinical trial show that the targeted radiation therapy 177Lutetium PSMA-617 (Lu-PSMA) significantly improved prostate-specific antigen (PSA) response compared with standard cabazitaxel in men with metastatic castration-resistant prostate cancer (CRPC) that progressed after docetaxel therapy. Read More ›

Oral relugolix given daily is superior to standard androgen-deprivation therapy (ADT) with leuprolide (Lupron) in men with advanced prostate cancer, according to the results of the phase 3 HERO study, which were reported at the ASCO 2020 virtual annual meeting and published online before the meeting (Shore ND, et al. N Engl J Med. Read More ›

There has been an increased focus on the study of tumor alterations that may predict treatment benefit or serve as possible actionable targets in cancer. During the virtual American Urological Association 2020 Annual Meeting, Kyrollis Attalla, MD, Urology Oncology Fellow, Memorial Sloan Kettering Cancer Center, Ridgewood, NY, discussed findings of a recent study that looked at the landscape of actionable genomic alterations and the corresponding evidence to support these alterations as predictive of response to targeted therapy in patients with renal-cell carcinoma (RCC). Read More ›

Nationally renowned oncologist Maurie Markman, MD, President of Medicine and Science at Cancer Treatment Centers of America, led a panel of experts in discussing how existing anticancer agents, such as kinase inhibitors and the corticosteroid dexamethasone, may be used for the treatment of patients with COVID-19 in a July webinar of the Association for Value-Based Cancer Care (AVBCC) on COVID-19. Read More ›

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